سرکار خانم دکتر سحر اسفندیاری

دکترای تخصصی بیولوژی تولید مثل

 

Education:

Department of Physiology and Biophysics, University of Illinois at Chicago, Chicago, Illinois, USA

Postdoctoral Fellow, 2020-Present

 

Departments of OBGYN (Obstetrics and Gynecology) and Surgery, University of Illinois at Chicago, Chicago, Illinois, USA

Visiting Research Scholar, 2019-2020

 

Department of Anatomy and Embryology, Tehran University of Medical Sciences, Tehran, Iran

Ph.D in Reproductive Biology, 2015-2020

 

Department of Veterinary, University of Tabriz, East Azerbaijan, Iran

Doctor of Veterinary, 2007-2014

 

Department of Veterinary, University of Tehran, Tehran, Iran

Visiting Research Scholar, 2013-2014

 

National Organization for Development of Exceptional Talents

High school Diploma, Experimental Sciences

 

Experiences:

  • Human Clinical Embryologist, Erfan Hospital (Givar Infertility Center) Tehran, Iran   2018-2019
  • Technical Supervisor, Ravan Sazeh Co (RS Medical), Tehran, Iran   2015-2019
  • Member of Scientific Board, Gena Medical Co, Tehran, Iran   2015-2019

 

Memberships:

  • American Society of Reproductive Medicine (ASRM)
  • Iraninan Society of Embryology and Reproductive Biology (ISERB)
  • Veterinary Council of Iran

 

Technical Skills:

Clinical Techniques

  • Assisted Reproductive Techniques for treatment of infertility (Human, Industrial Animals)
  • Sperm assessment, preparation techniques and cryopreservation
  • Testicular sperm preparation and evaluation
  • Routine andrology techniques
  • Oocyte retrieval and selection
  • Preparation of oocyte for Intracytoplasmic sperm injection (ICSI)
  • Intracytoplasmic sperm injection
  • In Vitro Fertilization (IVF)
  • Embryo culture, assessment and selection for transfer
  • Embryo transfer to Uterus
  • Embryo Assisted hatching by laser
  • Embryo biopsy for diagnosis of genetic disorders
  • Cryopreservation of sexual cells (oocyte and sperm)
  • Embryo Cryopreservation

Basic Research Techniques

  • System Biology (Immunoinformatics , Protein design and Protein- ligand docking)
  • Cell Culture (Bone Marrow Mesenchymal Stem cells, Ovarian cells, Spermatogonial stem cells)
  • Nested PCR
  • RT-PCR
  • DNA and RNA extraction
  • Exosome extraction
  • Nuclear and Cytoplasmic protein extraction
  • Western blotting
  • Flow cytometry
  • Immunohistochemistry
  • Immunocytochemistry
  • Data Analyzing

 

Research Interests:

Human and Industrial Animals reproduction and infertility:

  • Female Infertility (Idiopathic infertility, Endometriosis, Polycystic Ovarian Syndrome, Premature Ovarian Failure, Uterine Fibroid, Recurrent pregnancy loss, Gynecologic cancers, Sex hormones and Ovarian physiology, Oocyte aging)
  • Male Infertility
  • Granulosa cells, Exosomes
  • System biology in reproductive medicine
  • Different aspects of infertility

 

Publications:

Mesenchymal Stem Cells as a Bio Organ for Treatment of Female Infertility.

Esfandyari S, Chugh RM, Park HS, Hobeika E, Ulin M, Al-Hendy A. Cells. 2020 Oct;9(10):2253.

 

Evolving role of microRNAs in uterine fibroid pathogenesis: filling the gap!

Ali M, Esfandyari S, Al-Hendy A. Fertility and Sterility. 2020 Jun 1;113(6):1167-8.

 

The prevalence of latent and acute toxoplasmosis in HIV-infected pregnant women: A systematic review and meta-analysis.

Shiadeh MN, Esfandyari S, Ashrafmansouri M, Mirzapour A, Taghipour A, Spotin A, Arefkhah N, Gamble R, Safa A, Rostami A. 2020 Sep 30:104549.

 

Pyrvinium pamoate induces in-vitro suppression of IL-6 and IL-8 produced by human endometriotic stromal cells.

Karamian A, Paktinat S, Esfandyari S, Nazarian H, Ali Ziai S, Zarnani AH, Salehpour S, Hosseinirad H, Karamian A, Novin MG. Human & Experimental Toxicology. 2020 Oct 6:0960327120964543.

 

Isolation, identification and differentiation of human spermatogonial cells on three-dimensional decellularized sheep testis.

Movassagh SA, Movassagh SA, Dehkordi MB, Pourmand G, Gholami K, Talebi A, Esfandyari S, Jabari A, Samadian A, Abbasi M. Acta Histochemica. 2020 Dec 1;122(8):151623.

 

Designing and modeling of complex DNA vaccine based on tropomyosin protein of Boophilus genus tick.

Ranjbar MM, Gupta SK, Ghorban K, Nabian S, Sazmand A, Taheri M, Esfandyari S, Taheri M. Applied biochemistry and biotechnology. 2015 Jan 1;175(1):323-39.

 

SARS-CoV-2 seroprevalence worldwide: a systematic review and meta-analysis.

Rostami A, Sepidarkish M, Leeflang M, Riahi SM, Shiadeh MN, Esfandyari S, Mokdad AH, Hotez PJ, Gasser RB. Clinical Microbiology and Infection. 2020 Oct 24.

 

"“Begging the Question”—Does Toxocara Infection/Exposure Associate with Multiple
Sclerosis-Risk?"

Taghipour A, Rostami A, Esfandyari S, Aghapour S, Nicoletti A, Gasser RB. Pathogens. 2020 Nov;9(11):938.

 

A randomized exploratory trial to assess the effects of resveratrol on VEGF and TNF-a expression in endometriosis woman.

Khodarahmian M, Amidi F, Moini A, Kashani L, Salahi E, Danaii-mehrabad S, Nashtaei MS, Mojtahedi MF, Esfandyari S, Sobhani A. Journal of Reproductive Immunology. 2020 Nov 13:103248.

 

Editorial Activity

  • Stem cell Research and Therapy
  • Journal of Steroid Biochemistry and Molecular Biology 
  • Reproduction
  • Pediatrics and Neonatal Nursing
  • Medicina
  • Frontiers in Pharmacology
  • Genetic Testing and Molecular Biomarkers

 

Congresses:

MIRNA-92A SUPPRESSES ANDROGEN-PRODUCING STEROIDOGENIC GENES EXPRESSION IN H295R, A HUMAN PCOS IN-VITRO THECA-LIKE CELL. (Poster)

Esfandyari S, Fertility and Sterility. 2020 Sep 1;114(3):e349-50.

 

miRNA-144 INCREASES ESTROGEN-PRODUCING GENES EXPRESSION AND SUPPRESS APOPTOSIS IN HUMAN GRANULOSA CELL LINE. Fertility and Sterility. (Poster)

Esfandyari S. Fertility and Sterility. 2020 Sep 1;114(3):e438.

 

SAFETY AND TOXICOLOGY STUDY AFTER INTRA-OVARIAN ENGRAFTMENT OF HUMAN BONE MARROW MESENCHYMAL STEM CELL IN CHEMOTHERAPY INDUCED POI MOUSE MODEL. (Oral presentation)

Park HS, Chugh RM, Elsharoud A, Ulin M, Esfandyari S, Bakir L, Aboalsoud A, Al-Hendy A. Fertility and Sterility. 2020 Sep 1;114(3):e99-100.

 

MESENCHYMAL STEM CELLS SECRETOME REGULATES STEROIDOGENESIS AND DECREASES ANDROGEN PRODUCTION IN PCOS CELL MODEL VIA SECRETING BMP-2. (Poster)

Chugh RM, Park HS, Esfandyari S, Elsharoud A, Ulin M, Al-Hendy A. Fertility and Sterility. 2020 Sep 1;114(3):e403-4.

 

 

توجه! لطفا سوال خود از این دکتر را در اینجا مطرح کنید و برای ارسال سایر درخواست ها و پیام ها به بخش تماس با ما مراجعه فرمایید.